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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DYNC2H1 All Species: 21.82
Human Site: S2678 Identified Species: 48
UniProt: Q8NCM8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NCM8 NP_001073932 4307 492594 S2678 M H G A V L F S P K I S R G Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536596 4306 491933 S2678 M H G A V L F S P K I S R G Y
Cat Felis silvestris
Mouse Mus musculus Q45VK7 4306 492321 S2678 M H G A V L F S P K I S R G Y
Rat Rattus norvegicus Q9JJ79 4306 492200 S2678 M H G A V L F S P K I S R G Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509757 4391 500194 S2769 M H G A V L L S P K I S R G Y
Chicken Gallus gallus XP_417173 4301 491979 T2673 M H G A F L I T P K I S R G Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P37276 4639 530166 Q2945 M N G L S I F Q I K V H N K Y
Honey Bee Apis mellifera XP_395108 4023 452032 M2485 R K E D F S G M L E Q Y L Y Y
Nematode Worm Caenorhab. elegans Q19542 4171 473799 N2602 F S A K Q F D N E L K N A I T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36022 4092 471329 L2559 R H A A I L Y L G Y P S G K S
Red Bread Mold Neurospora crassa P45443 4367 495560 E2897 N Y V P V D R E Q L R D F V K
Conservation
Percent
Protein Identity: 100 N.A. N.A. 93.5 N.A. 93.3 93 N.A. 85.8 79.7 N.A. N.A. N.A. 26.4 30.3 40.7 N.A.
Protein Similarity: 100 N.A. N.A. 96.5 N.A. 97.1 97 N.A. 91.8 89.4 N.A. N.A. N.A. 47.8 52.5 61.2 N.A.
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 93.3 80 N.A. N.A. N.A. 33.3 6.6 0 N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 93.3 86.6 N.A. N.A. N.A. 53.3 13.3 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.8 27.6
Protein Similarity: N.A. N.A. N.A. N.A. 44.3 48.2
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 40 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 19 64 0 0 0 0 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 10 10 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 10 0 0 0 0 10 10 10 0 0 0 0 0 % E
% Phe: 10 0 0 0 19 10 46 0 0 0 0 0 10 0 0 % F
% Gly: 0 0 64 0 0 0 10 0 10 0 0 0 10 55 0 % G
% His: 0 64 0 0 0 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 0 10 10 10 0 10 0 55 0 0 10 0 % I
% Lys: 0 10 0 10 0 0 0 0 0 64 10 0 0 19 10 % K
% Leu: 0 0 0 10 0 64 10 10 10 19 0 0 10 0 0 % L
% Met: 64 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 10 10 0 0 0 0 0 10 0 0 0 10 10 0 0 % N
% Pro: 0 0 0 10 0 0 0 0 55 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 0 10 10 0 10 0 0 0 0 % Q
% Arg: 19 0 0 0 0 0 10 0 0 0 10 0 55 0 0 % R
% Ser: 0 10 0 0 10 10 0 46 0 0 0 64 0 0 10 % S
% Thr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 10 % T
% Val: 0 0 10 0 55 0 0 0 0 0 10 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 10 0 0 10 0 10 0 10 73 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _